CD2314
CD2314 is a potent and selective RARβ receptor agonist with a Kd of 195 nM in S91 melanoma cells[1].
Product Specifications
CAS Number
[170355-37-0]
UNSPSC
12352005
Target
RAR/RXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cd2314.html
Concentration
10mM
Purity
99.84
Solubility
DMSO : 83.33 mg/mL (ultrasonic)
Smiles
O=C(C1=CSC(C2=CC=C3C=C4C(C)(C)CCC(C)(C)C4=CC3=C2)=C1)O
Molecular Formula
C23H24O2S
Molecular Weight
364.50
References & Citations
[1]Spanjaard RA, et al. Specific activation of retinoic acid receptors (RARs) and retinoid X receptors reveals a unique role for RARgamma in induction of differentiation and apoptosis of S91 melanoma cells. J Biol Chem. 1997 Jul 25;272 (30) :18990-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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