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SR15006

Product Specifications

UNSPSC Description

SR15006 is a inhibitor of Krüppel-like factor 5 (KLF5) with an IC50 of 41.6 nM in DLD-1/pGL4.18hKLF5p cells)[1].

Target Antigen

KLF

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sr15006.html

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NCC(N1CCN(S(=O)(C)=O)CC1)=O)/C=C/C2=CC=CC(Cl)=C2

Molecular Weight

385.87

References & Citations

[1]Kim J, et al. The Novel Small-Molecule SR18662 Efficiently Inhibits the Growth of Colorectal Cancer In Vitro and In Vivo. Mol Cancer Ther. 2019;18(11):1973-1984.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-139691/SR15006-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-139691/SR15006-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2505001-54-5

Available Sizes

Curated Selection

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