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Endothelin Receptor Antibody

Getagozumab is a humanized IgG4-kappa monoclonal antibody that specifically targets endothelin receptor type A (EDNRA) with potent antagonistic activity. Getagozumab significantly lowered pulmonary arterial pressure in both hypoxia-induced and monocrotaline (MCT) -induced pulmonary arterial hypertension (PAH) monkey models and further attenuated the associated pulmonary arterial and right ventricular hypertrophy.

Product Specifications

Product Name Alternative

Patecibart, GMA301, GMA-301

Target

Endothelin Receptor

Clonality

Monoclonal

Conjugation

Unconjugated

Field of Research

Pharmacology & Drug Discovery

Concentration

5.49 mg/mL

Purity

95.90% (May vary between batches)

Molecular Weight

145.28 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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