Endothelin Receptor Antibody
Getagozumab is a humanized IgG4-kappa monoclonal antibody that specifically targets endothelin receptor type A (EDNRA) with potent antagonistic activity. Getagozumab significantly lowered pulmonary arterial pressure in both hypoxia-induced and monocrotaline (MCT) -induced pulmonary arterial hypertension (PAH) monkey models and further attenuated the associated pulmonary arterial and right ventricular hypertrophy.
Product Specifications
Product Name Alternative
Patecibart, GMA301, GMA-301
Target
Endothelin Receptor
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Pharmacology & Drug Discovery
Concentration
5.49 mg/mL
Purity
95.90% (May vary between batches)
Molecular Weight
145.28 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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