EGFR Antibody
CDX-3379 is a humanized monoclonal antibody inhibitor that targets ErbB3. By binding to ErbB3, CDX-3379 prevents its dimerization with other receptors, thus inhibiting ErbB3 phosphorylation. This compound can also inhibit the growth and proliferation of tumor cells. CDX-3379 shows potential for research in tumors expressing ErbB3 and NRG1, such as those found in HNSCC.
Product Specifications
Target
EGFR
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
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