ZB-R-55
ZB-R-55 is an orally active RIPK1 inhibitor. ZB-R-55 can be used for sepsis study[1].
Product Specifications
CAS Number
[2416593-55-8]
UNSPSC
12352005
Target
RIP kinase
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/zb-r-55.html
Purity
99.39
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN1C2=CC(C#CC3CC3)=CC=C2OC[C@H](NC(C4=NC(CC5=CC=CC=C5)=NN4)=O)C1=O
Molecular Formula
C25H23N5O3
Molecular Weight
441.48
References & Citations
[1]Yang X, et al. Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis. Angew Chem Int Ed Engl. 2022;61 (5) :e202114922.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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