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GDNF Antibody: Biotin

Product Specifications

Gene Name

[GDNF]

NCBI Gene ID

2668

Reactivity

Human, Mouse, Rat

Storage Conditions

Conjugated antibodies should be stored according to the product label

Specificity

Detects monomeric and homodimeric GDNF<br>Tissue Specificity: In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change.

Other Gene Names

[GDNF; GDNF; ATF1; ATF2; HSCR3; HFB1-GDNF; hGDNF; ATF]

Short Name

[GDNF]

Other Product Names

[glial cell line-derived neurotrophic factor isoform 1 preproprotein; Glial cell line-derived neurotrophic factor; glial cell line-derived neurotrophic factor; ATF; astrocyte-derived trophic factor; glial cell derived neurotrophic factor; Astrocyte-derived trophic factor]

NCBI Accession Number

NP_000505.1

NCBI GB Accession Number

NM_000514.3

Uniprot Accession Number

P39905

Available Sizes

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