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CVT-11127

CVT-11127 is a potent SCD inhibitor. CVT-11127 induces apoposis and arrests the cell cycle at the G1/S phase. CVT-11127 has the potential for the research of lung cancer[1].

Product Specifications

CAS Number

[1018674-83-3]

Product Name Alternative

GS-456332

UNSPSC

12352209

Target

Apoptosis; Stearoyl-CoA Desaturase (SCD)

Type

Peptides

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cvt-11127.html

Purity

99.94

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

CC(NCCN1C2=NC(NCC3=CC=C(C(Cl)=C3)Cl)=CC=C2N=C(C1=O)C4=CC=C(C=C4)OC)=O

Molecular Formula

C25H23Cl2N5O3

Molecular Weight

512.39

References & Citations

[1]Hess D, et al. Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells. PLoS One. 2010; 5 (6) :e11394.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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