NVP-BAG956
NVP-BAG956 is an ATP-competitive PI3K inhibitor with IC50s of 34, 56, 112 and 444 nM for PI3Kδ, PI3Kα, PI3Kγ and PI3Kβ, respectively.
Product Specifications
CAS Number
[853910-02-8]
Product Name Alternative
BAG 956
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nvp-bag956.html
Purity
99.21
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC1=NC2=C(C3=CC(C#CC4=CC=CN=C4)=CC=C3N=C2)N1C5=CC=C(C=C5)C(C#N)(C)C
Molecular Formula
C28H21N5
Molecular Weight
427.50
References & Citations
[1]Marone R, et al. Targeting melanoma with dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitors. Mol Cancer Res. 2009 Apr;7 (4) :601-13.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6287706-01 0.2 mL
COL4A5, NT (COL4A5, Collagen alpha-5(IV) chain) (Azide free) (HRP)
Ask
View Details MBS6287706-02 5x 0.2 mL
COL4A5, NT (COL4A5, Collagen alpha-5(IV) chain) (Azide free) (HRP)
Ask
View Details 
132342-ML405 100 µL
RASGRP2 (RAS Guanyl-releasing Protein 2, Calcium and DAG-regulated Guanine Nucleotide Exchange Factor I, CalDAG-GEFI, Cdc25-like Protein, CDC25L, hCDC25L, F25B3.3 Kinase-like Protein, MCG7) (MaxLight 405) discontinued
Ask
View Details