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Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10)

Selected Variant

HY-P990117-01

Size: 1 mg

Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) is a mouse-derived Osteopontin/SPP1 IgG1 κ type antibody inhibitor. Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) blocks Angiotensin II -induced DNA synthesis and collagen gel contraction in cardiac fibroblasts. Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) significantly inhibits tumor growth in CT26 or MC38 tumors mice models[1][2][3].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

Integrin

Type

Inhibitory Antibodies

Related Pathways

Cytoskeleton

Field of Research

Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/anti-mouse-rat-human-osteopontin-spp1-antibody-mpiiib10.html

Purity

95.00

Solubility

10 mM in DMSO

Smiles

[Anti-Mouse/Rat/HumanOsteopontin/SPP1Antibody(MPIIIB10)]

Molecular Weight

(150 kDa)

References & Citations

[1]Kim EK, et al. Tumor-derived osteopontin suppresses antitumor immunity by promoting extramedullary myelopoiesis. Cancer Res. 2014 Nov 15;74 (22) :6705-16.|[2]Ashizawa N, et al. Osteopontin is produced by rat cardiac fibroblasts and mediates A (II) -induced DNA synthesis and collagen gel contraction. J Clin Invest. 1996 Nov 15;98 (10) :2218-27.|[3]Kim JY, et al. Echinochrome A inhibits HMGB1-induced vascular smooth muscle cell migration by suppressing osteopontin expression. Korean J Physiol Pharmacol. 2025 Jan 1;29 (1) :83-92.

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4°C for 2 years, do not freeze

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

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