MrgprX2 antagonist-4
Product Specifications
UNSPSC Description
MrgprX2 antagonist-4 is an MrgprX2 antagonist extracted from patent US20210128561A1, compound B-51 E117. MrgprX2 antagonist-4 can be used for the research of inflammatory disorders of the skin[1].
Target Antigen
Mas-related G-protein-coupled Receptor (MRGPR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mrgprx2-antagonist-4.html
Solubility
DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C1C(CC)=C(C(C)C)N=C2NC3=CC=C(C)C=C3N12
Molecular Weight
269.34
References & Citations
[1]Müller C, et, al. MRGX Receptor Antagonists. US20210128561A1.|[2]Porebski G, et, al. Mas-Related G Protein-Coupled Receptor-X2 (MRGPRX2) in Drug Hypersensitivity Reactions. Front Immunol. 2018 Dec 20;9:3027.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-145194/MrgprX2-antagonist-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-145194/MrgprX2-antagonist-4-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2641398-04-9
Available Sizes
Curated Selection
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