Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

CCT020312

CCT020312 is a selective EIF2AK3/PERK activator. CCT020312 elicits EIF2A phosphorylation in cells.

Product Specifications

CAS Number

[324759-76-4]

Product Name Alternative

2'-3'-cyclic GMP-AMP

UNSPSC

12352005

Target

Autophagy; PERK

Type

Reference compound

Related Pathways

Autophagy; Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/CCT020312.html

Concentration

10mM

Purity

99.05

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1NC2=C(C(C3=CC=CC=C3)=C1C4=NN(C(C4)C5=CC=C(C=C5)Br)C(CCN(CC)CC)=O)C=C(C=C2)Br

Molecular Formula

C31H30Br2N4O2

Molecular Weight

650.40

References & Citations

[1]Stockwell SR, et al.Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling. PLoS One. 2012;7 (1) :e28568.|[2]Bruch J, et al. PERK activation mitigates tau pathology in vitro and in vivo. EMBO Mol Med. 2017 Mar;9 (3) :371-384.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

More Discoveries

Explore Other Products

Browse additional items from our catalog

ZNF238 (Zinc Finger Protein 238, Zinc Finger and BTB Domain-containing Protein 18, ZBTB18, 58kD Repressor Protein, RP58, Transcriptional Repressor RP58, Translin-associated Zinc Finger Protein 1, TAZ1, TAZ-1, Zinc Finger Protein C2H2-171) (FITC)

MBS6150562-01 0.1 mL

ZNF238 (Zinc Finger Protein 238, Zinc Finger and BTB Domain-containing Protein 18, ZBTB18, 58kD Repressor Protein, RP58, Transcriptional Repressor RP58, Translin-associated Zinc Finger Protein 1, TAZ1, TAZ-1, Zinc Finger Protein C2H2-171) (FITC)

Sign In for Pricing

ZNF238 (Zinc Finger Protein 238, Zinc Finger and BTB Domain-containing Protein 18, ZBTB18, 58kD Repressor Protein, RP58, Transcriptional Repressor RP58, Translin-associated Zinc Finger Protein 1, TAZ1, TAZ-1, Zinc Finger Protein C2H2-171) (FITC)

MBS6150562-02 5x 0.1 mL

ZNF238 (Zinc Finger Protein 238, Zinc Finger and BTB Domain-containing Protein 18, ZBTB18, 58kD Repressor Protein, RP58, Transcriptional Repressor RP58, Translin-associated Zinc Finger Protein 1, TAZ1, TAZ-1, Zinc Finger Protein C2H2-171) (FITC)

Sign In for Pricing

Rabbit Monoclonal ABHD14B Antibody (002) [DyLight 755]

NBP2-90259IR 0.1 mL

Rabbit Monoclonal ABHD14B Antibody (002) [DyLight 755]

Sign In for Pricing

pCDH-CMV-THBS1-N708A-EF1a-turboRFP-T2A-Puro Plasmid

PVT38559 2 µg

pCDH-CMV-THBS1-N708A-EF1a-turboRFP-T2A-Puro Plasmid

Sign In for Pricing

Nuclear Matrix Protein p84 (THOC1) Human shRNA Plasmid Kit (Locus ID 9984)

TL308836 1 Kit

Nuclear Matrix Protein p84 (THOC1) Human shRNA Plasmid Kit (Locus ID 9984)

Sign In for Pricing

FHIT (Fragile Histidine Triad Gene, AP3Aase, FRA3B) (MaxLight 650)

MBS6227542-01 0.1 mL

FHIT (Fragile Histidine Triad Gene, AP3Aase, FRA3B) (MaxLight 650)

Sign In for Pricing