6'-O-beta-D-Glucosylgentiopicroside

6'-O-beta-D-Glucosylgentiopicroside is a secoiridoid isolated from the roots of G. straminea. 6'-O-beta-D-Glucosylgentiopicroside strongly suppresses N-formyl-methionyl-leucyl-phenylalanine (fMLP) -induced superoxide generation[1].

Product Specifications

CAS Number

[115713-06-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/6-o-beta-d-glucosylgentiopicroside.html

Purity

98.24

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C=C[C@@H]([C@@H]1O[C@]([C@@H]([C@@H](O)[C@@H]2O)O)([H])O[C@@H]2CO[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO)C(C4=CO1)=CCOC4=O

Molecular Formula

C22H30O14

Molecular Weight

518.47

Precautions

H302, H315, H319, H335

References & Citations

[1]Wei S, et al. Inhibitory effects of secoiridoids from the roots of Gentiana straminea on stimulus-induced superoxide generation, phosphorylation and translocation of cytosolic compounds to plasma membrane in human neutrophils. Phytother Res. 2012 Feb;26 (2) :168-73.