NOSTN rabbit pAb
Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production. [supplied by OMIM, Apr 2004],
Product Specifications
Background
Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.[supplied by OMIM, Apr 2004]
UniProt
Q8IVI9
Swiss Prot
Q8IVI9
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human NOSTN AA range: 309-359
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1: 500-2000
Storage Conditions
-20°C/1 year
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES14467-1.pdf
Fragment
IgG
Subcellular Location
[Isoform 1]: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasmic vesicle . Cytoplasm, cytoskeleton . Enriched in selected actin structures (PubMed:16234328, PubMed:16376344) .; [Isoform 3]: Nucleus .
Gene ID (Human)
115677
Available Sizes
Curated Selection
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