JS6
JS6 is a Bcl3 inhibitor, and inhibits Bcl3-NF-kB1 binding. JS6 inhibits tumor cell growth in vitro and in vivo[1].
Product Specifications
CAS Number
950244-33-4
UNSPSC
12352005
Target
NF-κB
Type
Reference compound
Related Pathways
NF-κB
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/js6.html
Purity
99.67
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(NCCN1CCOCC1)C2=CC=CC=C2NC(C3=CC=CC=C3F)=O
Molecular Formula
C20H22FN3O3
Molecular Weight
371.41
References & Citations
[1]Soukupová J, et al. The Discovery of a Novel Antimetastatic Bcl3 Inhibitor. Mol Cancer Ther. 2021;20 (5) :775-786.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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