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JS6

JS6 is a Bcl3 inhibitor, and inhibits Bcl3-NF-kB1 binding. JS6 inhibits tumor cell growth in vitro and in vivo[1].

Product Specifications

CAS Number

950244-33-4

UNSPSC

12352005

Target

NF-κB

Type

Reference compound

Related Pathways

NF-κB

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/js6.html

Purity

99.67

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(NCCN1CCOCC1)C2=CC=CC=C2NC(C3=CC=CC=C3F)=O

Molecular Formula

C20H22FN3O3

Molecular Weight

371.41

References & Citations

[1]Soukupová J, et al. The Discovery of a Novel Antimetastatic Bcl3 Inhibitor. Mol Cancer Ther. 2021;20 (5) :775-786.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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