TRULI
Product Specifications
UNSPSC Description
TRULI (Lats-IN-1) is a potent and ATP-competitive inhibitor of Lats1 and Lats2 kinases. TRULI promotes Yap-dependent proliferation in postmitotic mammalian tissues[1].
Target Antigen
YAP
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/truli.html
Smiles
O=C(C1=CNC2=NC=CC=C12)/N=C(SC=C3)/N3CC4=CC=CC=C4
Molecular Weight
334.39
References & Citations
[1]Nathaniel Kastan, et al. Small-molecule inhibition of Lats kinases promotes Yap-dependent proliferation in postmitotic mammalian tissues. bioRxiv 2020.02.11.944157.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-138489/TRULI-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-138489/TRULI-SDS-MedChemExpress.pdf
CAS Number
1424635-83-5
Available Sizes
Curated Selection
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