Picroside I
Product Specifications
UNSPSC Description
Picroside I is the major ingredient of Picrorhiza scrophulariiflora. Picrorhiza scrophulariiflora is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside-I and Picroside-II[1]. Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose-dependently increases the serum levels of IFN-γ[2].
Target Antigen
STAT
Type
Natural Products
Related Pathways
JAK/STAT Signaling;Stem Cell/Wnt
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/picroside-i.html
Purity
99.55
Solubility
DMSO : 250 mg/mL (ultrasonic)|H2O : 116.67 mg/mL (ultrasonic)
Smiles
OC[C@]12[C@@H](O2)[C@@H](O)[C@@]3([H])[C@]1([H])[C@H](O[C@]4([H])O[C@H](COC(/C=C/C5=CC=CC=C5)=O)[C@@H](O)[C@H](O)[C@H]4O)OC=C3
Molecular Weight
492.47
References & Citations
[1]Ganeshkumar Y, et al. Picroside I and Picroside II from Tissue Cultures of <i>Picrorhiza kurroa</i>. Pharmacognosy Res. 2017 Dec;9(Suppl 1):S53-S56.|[2]Sen Zhang, et al. Picroside I inhibits asthma phenotypes by regulating Tbet/GATA-3 ratio and Th1/Th2 balance in a murine model of asthma. Tropical Journal of Pharmaceutical Research September 2018; 17 (9): 1777-1782.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N0407/Picroside-I-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N0407/Picroside-I-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
27409-30-9
Available Sizes
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