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TRAILR4/TNFRSF10D, Rhesus Macaque (HEK293, His)

TRAILR4/TNFRSF10D Protein , a receptor for TRAIL. Paradoxically, it not only fails to induce apoptosis but also protects against TRAIL-mediated apoptosis. Conflicting reports exist about its role in activating the NF-kappa-B pathway. The dual nature of TRAILR4 in interacting with TRAIL, both as a receptor and a protective factor, highlights the complexity of its regulatory functions in cellular responses to TRAIL signaling. TRAILR4/TNFRSF10D Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived TRAILR4/TNFRSF10D protein, expressed by HEK293 , with C-His labeled tag.

Product Specifications

Product Name Alternative

TRAILR4/TNFRSF10D Protein, Rhesus Macaque (HEK293, His), Rhesus Macaque, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/trailr4-tnfrsf10d-protein-rhesus-macaque-hek293-his.html

Purity

95.00

Smiles

ATISRKDEVPLPPVASKQQRRSLEAECPAGFHRSEHTGACNPCTEGVDYTIASNNLPSCLLCTVCKSGQTNTSSCTTTRDTVCQCEKGSFQDANSPEMCRKCSTGCPRGMIKVSDCTPWSDINCSASAASSTGKTPAAEDTVPTSLGTPDL

Molecular Formula

716901 (Gene_ID) XP_001107922 (A56-L206) (Accession)

Molecular Weight

Approximately 22-32 kDa due to the glycosylation.

References & Citations

[1]Degli-Esposti MA, et al. The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. Immunity. 1997 Dec;7 (6) :813-20.|[2]Pan G, et al. TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling. FEBS Lett. 1998 Mar 6;424 (1-2) :41-5.|[3]Marsters SA, et al. A novel receptor for Apo2L/TRAIL contains a truncated death domain. Curr Biol. 1997 Dec 1;7 (12) :1003-6.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Storage Conditions

Stored at -20°C for 2 years

Scientific Category

Recombinant Proteins

Available Sizes

Frequently Asked Questions

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