Elsinochrome A
Product Specifications
UNSPSC Description
Elsinochrome A is a perylene quinone photosensitizer, and can generate reactive oxygen species (ROS) to induce apoptosis and autophagy under light excitation. Elsinochrome A also shows antifungal activity against C. albicans biofilm through photodynamic antimicrobial chemotherapy (PACT). Elsinochrome A can be used for research of photodynamic therapy (PDT) (Ex: 460 nm)[1][2].
Target Antigen
Apoptosis; Autophagy; Fluorescent Dye; Fungal; Reactive Oxygen Species
Type
Dye Reagents
Related Pathways
Anti-infection;Apoptosis;Autophagy;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB;Others
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/elsinochrome-a.html
Solubility
10 mM in DMSO
Smiles
CC([C@H]1C(C2=C(C3=C(C=C4OC)O)C4=C(C(OC)=CC(O)=C56)C5=C2C([C@@H]1C(C)=O)=C(OC)C6=O)=C(OC)C3=O)=O
Molecular Weight
544.51
References & Citations
[1]Yao Y, et al. Elsinochrome A induces cell apoptosis and autophagy in photodynamic therapy. J Cell Biochem. 2023 Sep;124(9):1346-1365. |[2]Pan L, et al. Inhibitory Effects and Mechanism of Action of Elsinochrome A on Candida albicans and Its Biofilm. J Fungi (Basel). 2022 Aug 11;8(8):841.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N10611/Elsinochrome-A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N10611/
Clinical Information
No Development Reported
CAS Number
24568-67-0
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