Elsinochrome A

Elsinochrome A is a perylene quinone photosensitizer, and can generate reactive oxygen species (ROS) to induce apoptosis and autophagy under light excitation. Elsinochrome A also shows antifungal activity against C. albicans biofilm through photodynamic antimicrobial chemotherapy (PACT) . Elsinochrome A can be used for research of photodynamic therapy (PDT) (Ex: 460 nm) [1][2].

Product Specifications

CAS Number

[24568-67-0]

UNSPSC

12171500

Target

Apoptosis; Autophagy; Fluorescent Dye; Fungal; Reactive Oxygen Species (ROS)

Type

Dye Reagents

Related Pathways

Anti-infection; Apoptosis; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/elsinochrome-a.html

Solubility

10 mM in DMSO

Smiles

CC([C@H]1C(C2=C(C3=C(C=C4OC)O)C4=C(C(OC)=CC(O)=C56)C5=C2C([C@@H]1C(C)=O)=C(OC)C6=O)=C(OC)C3=O)=O

Molecular Formula

C30H24O10

Molecular Weight

544.51

References & Citations

[1]Yao Y, et al. Elsinochrome A induces cell apoptosis and autophagy in photodynamic therapy. J Cell Biochem. 2023 Sep;124 (9) :1346-1365. |[2]Pan L, et al. Inhibitory Effects and Mechanism of Action of Elsinochrome A on Candida albicans and Its Biofilm. J Fungi (Basel) . 2022 Aug 11;8 (8) :841.