4,6-Dioxoheptanoic acid

4,6-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis.

Product Specifications

CAS Number

[51568-18-4]

Product Name Alternative

Succinylacetone

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/4,6-Dioxoheptanoic_acid.html

Purity

98.81

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

CC(=O)CC(=O)CCC(O)=O

Molecular Formula

C7H10O4

Molecular Weight

158.15

Precautions

H315, H319, H335

References & Citations

[1]Ebert PS, et al. Succinylacetone, a potent inhibitor of heme biosynthesis: effect on cell growth, heme contentand delta-aminolevulinic acid dehydratase activity of malignant murine erythroleukemia cells. Biochem Biophys Res Commun. 1979 Jun 27;88 (4) :1382-90.