4,6-Dioxoheptanoic acid
4,6-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis.
Product Specifications
CAS Number
[51568-18-4]
Product Name Alternative
Succinylacetone
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/4,6-Dioxoheptanoic_acid.html
Purity
98.81
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
CC(=O)CC(=O)CCC(O)=O
Molecular Formula
C7H10O4
Molecular Weight
158.15
Precautions
H315, H319, H335
References & Citations
[1]Ebert PS, et al. Succinylacetone, a potent inhibitor of heme biosynthesis: effect on cell growth, heme contentand delta-aminolevulinic acid dehydratase activity of malignant murine erythroleukemia cells. Biochem Biophys Res Commun. 1979 Jun 27;88 (4) :1382-90.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
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