Arginase inhibitor 1
Product Specifications
UNSPSC Description
Arginase inhibitor 1 is a potent inhibitor of human arginases I and II with IC50s of 223 and 509 nM, respectively.
Target Antigen
Arginase
Type
Reference compound
Related Pathways
Immunology/Inflammation;Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Arginase-inhibitor-1.html
Solubility
DMSO : ≥ 48 mg/mL|H2O : ≥ 30 mg/mL
Smiles
O=C(O)[C@@](CCN1CCCCC1)(N)CCCCB(O)O
Molecular Weight
286.18
References & Citations
[1]Van Zandt MC, et al. Discovery of (R)-2-amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic acid and congeners as highly potentinhibitors of human arginases I and II for treatment of myocardial reperfusion injury. J Med Chem. 2013 Mar 28;56(6):2568-80.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-15775/Arginase-inhibitor-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15775/Arginase-inhibitor-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1345808-25-4
Available Sizes
Curated Selection
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