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Arginase inhibitor 1

Product Specifications

UNSPSC Description

Arginase inhibitor 1 is a potent inhibitor of human arginases I and II with IC50s of 223 and 509 nM, respectively.

Target Antigen

Arginase

Type

Reference compound

Related Pathways

Immunology/Inflammation;Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Arginase-inhibitor-1.html

Solubility

DMSO : ≥ 48 mg/mL|H2O : ≥ 30 mg/mL

Smiles

O=C(O)[C@@](CCN1CCCCC1)(N)CCCCB(O)O

Molecular Weight

286.18

References & Citations

[1]Van Zandt MC, et al. Discovery of (R)-2-amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic acid and congeners as highly potentinhibitors of human arginases I and II for treatment of myocardial reperfusion injury. J Med Chem. 2013 Mar 28;56(6):2568-80.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-15775/Arginase-inhibitor-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-15775/Arginase-inhibitor-1-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1345808-25-4

Available Sizes

Curated Selection

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