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IEM-1460

IEM-1460 blocks both AMPA and NMDA glutamate receptor with anticonvulsant effect in vivo[1].

Product Specifications

CAS Number

121034-89-7

UNSPSC

12352211

Hazard Statement

H315-H319-H335

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/iem-1460.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C[N+](C)(C)CCCCCNCC12C[C@H](C3)C[C@H](C[C@H]3C2)C1.Br.[Br-]

Molecular Formula

C19H38Br2N2

Molecular Weight

454.33

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Schlesinger F, et al. Two mechanisms of action of the adamantane derivative IEM-1460 at human AMPA-type glutamate receptors. Br J Pharmacol. 2005 Jul;145 (5) :656-63.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

AMPA Receptor

Available Sizes

Frequently Asked Questions

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