C3TD879
C3TD879 is a Type I kinase inhibitor that potently inhibits CITK catalytic activity (IC50 = 12 nM) . C3TD879 binds directly to full-length human CITK in cells (NanoBRET Kd [1].
Product Specifications
CAS Number
2850259-33-3
UNSPSC
12352005
Target
Ser/Thr Protease
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/c3td879.html
Purity
99.42
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=CC(NC([C@H](N)CC(C)(C)C)=O)=CC=C1C2=C3C(NC(C)=C3)=NC=C2
Molecular Formula
C22H28N4O
Molecular Weight
364.48
References & Citations
[1]Maw JJ, et al. Discovery and Characterization of Selective, First-in-Class Inhibitors of Citron Kinase. J Med Chem. 2024 Feb 22;67 (4) :2631-2666.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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