Clindamycin (hydrochloride)
Clindamycin (hydrochloride) is a semisynthetic lincosamide antibiotic, which inhibits protein synthesis by acting on the 50S ribosomal.
Product Specifications
CAS Number
21462-39-5
UNSPSC
12352005
Hazard Statement
H317, H319, H362
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/clindamycin-hydrochloride.html
Purity
99.91
Solubility
DMSO : ≥ 100 mg/mL|H2O : ≥ 100 mg/mL
Smiles
C[C@H](Cl)[C@@]([C@@]([C@@H]([C@H](O)[C@H]1O)O)([H])O[C@@H]1SC)([H])NC([C@@H]2C[C@@H](CCC)CN2C)=O.Cl
Molecular Formula
C18H34Cl2N2O5S
Molecular Weight
461.44
Precautions
H317, H319, H362
References & Citations
[1]Batzias GC, et al. Clindamycin bioavailability and pharmacokinetics following oral administration of clindamycin hydrochloride capsules in dogs. Vet J. 2005 Nov;170 (3) :339-45.|[2]Warrick JM, et al. Effect of clindamycin hydrochloride on oral malodor, plaque, calculus, and gingivitis in dogs with periodontitis. Vet Ther. 2000 Winter;1 (1) :5-16.|[3]Nielsen D, et al. Effects of treatment with clindamycin hydrochloride on progression of canine periodontal disease after ultrasonic scaling. Vet Ther. 2000 Summer;1 (3) :150-8.|[4]Bloom PB, et al. Efficacy of once-daily clindamycin hydrochloride in the treatment of superficial bacterial pyoderma in dogs. J Am Anim Hosp Assoc. 2001 Nov-Dec;37 (6) :537-42.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
BioRxiv. 2024 Jan 18.|bioRxiv. 2024 May 10.|ACS Environ Au. 2025 Aug 8.|ACS Omega. 2022 Mar 3;7 (10) :9004-9014.|Acta Pharm Sin B. 2021 Sep;11 (9) :2850-2858.|Anal Chem. 2025 Jun 3;97 (21) :11099-11109.|Dermatol Clin. 2024 September 12.|Diagn Microbiol Infect Dis. 2025 Nov 4;114 (2) :117181.|EBioMedicine. 2022 Apr;78:103943.|Future Microbiol. 2025 Oct 13:1-10.|Microbiol Spectr. 2025 Oct 15:e0122125.|Water Res. 2023 Jul 15:240:120110.|EBioMedicine. 2022 Apr;78:103943.|Tissue Cell. 2025 Jan 25:93:102759.
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