Notoginsenoside R2

Notoginsenoside R2 is a newly isolated notoginsenoside from Panax notoginseng, showed neuroprotective effects against 6-OHDA-induced oxidative stress and apoptosis.

Product Specifications

CAS Number

[80418-25-3]

Product Name Alternative

20 (S) -Notoginsenoside R2; Ginsenoside Ng-R2

UNSPSC

12352005

Hazard Statement

H302

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Notoginsenoside-R2.html

Purity

98.78

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C[C@]([C@@](C[C@H]1O)([H])[C@]2(CC[C@@H]3O)C)(C[C@H](O[C@@](O[C@H](CO)[C@@H](O)[C@@H]4O)([H])[C@@H]4O[C@@](OC[C@@H](O)[C@@H]5O)([H])[C@@H]5O)[C@@]2([H])C3(C)C)[C@]6([C@@]1([H])[C@]([C@@](C)(O)CC/C=C(C)/C)([H])CC6)C

Molecular Formula

C41H70O13

Molecular Weight

770.99

Precautions

H302

References & Citations

[1]Meng XB, et al. P90RSK and Nrf2 Activation via MEK1/2-ERK1/2 Pathways Mediated by Notoginsenoside R2 to Prevent 6-Hydroxydopamine-Induced Apoptotic Death in SH-SY5Y Cells. Evid Based Complement Alternat Med. 2013;2013:971712.|[2]González-Burgos E, et al. Potential neuroprotective activity of Ginseng in Parkinson's disease: a review. J Neuroimmune Pharmacol. 2015 Mar;10 (1) :14-29.