β-cyano-L-Alanine

β-cyano-L-Alanine (Beta-cyano-l-alanine), a nitrile of widespread occurrence in higher plants, is enzymatically produced by cyanoalanine synthase from cyanide and cysteine as substrates[1]. β-cyano-L-Alanine abolishes the protective effect of ethanol on cerebral ischemia/reperfusion (I/R) injury[2].

Product Specifications

CAS Number

[6232-19-5]

Product Name Alternative

Beta-cyano-l-alanine

UNSPSC

12352211

Hazard Statement

H301, H311, H331

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/beta-cyano-l-alanine.html

Purity

99.900

Solubility

H2O : 20.83 mg/mL (ultrasonic)

Smiles

N[C@@H](CC#N)C(O)=O

Molecular Formula

C4H6N2O2

Molecular Weight

114.10

Precautions

H301, H311, H331

References & Citations

[1]Piotrowski M, et al. The Arabidopsis thaliana isogene NIT4 and its orthologs in tobacco encode beta-cyano-L-alanine hydratase/nitrilase.J Med Chem. J Biol Chem. 2001 Jan 26;276 (4) :2616-21.|[2]McCarter KD, et al. Influence of low-dose alcohol consumption on post-ischemic inflammation: Role of cystathionine γ-lyase. Alcohol. 2019 May;76:81-89.