4,4-Diphenylbutylamine (hydrochloride)
4,4-Diphenylbutylamine shows affinity for the 5-HT2A and H1 receptors with Kis of 2589 and 1670 nM, respectively[1].
Product Specifications
CAS Number
[22101-90-2]
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/4-4-diphenylbutylamine-hydrochloride.html
Purity
99.00
Solubility
DMSO : 66.67 mg/mL (ultrasonic)
Smiles
NCCCC(C1=CC=CC=C1)C2=CC=CC=C2.[H]Cl
Molecular Formula
C16H20ClN
Molecular Weight
261.79
References & Citations
[1]Shah JR, et al. Synthesis, structure-affinity relationships, and modeling of AMDA analogs at 5-HT2A and H1 receptors: structural factors contributing to selectivity. Bioorg Med Chem. 2009;17 (18) :6496-6504.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor
Available Sizes
Curated Selection
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