Closed-HMRG
Closed-HMRG is HMRG with closed spirocyclic structure. Ac-HMRG, an acetylated derivative of Hydroxymethyl rhodamine green, exists as a closed spirocyclic structure in aqueous solution at physiological pH, whereas HMRG itself takes an open nonspirocyclic structure. Ac-HMRG is colorless and nonfluorescent and HMRG is strongly fluorescent[1].
Product Specifications
CAS Number
7449-51-6
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Assay Protocol
https://www.medchemexpress.com/closed-hmrg.html
Smiles
NC1=CC=C2C(OC3=CC(N)=CC=C3C24OCC5=C4C=CC=C5)=C1
Molecular Formula
C20H16N2O2
Molecular Weight
316.35
References & Citations
[1]Masayo Sakabe, et al. Rational design of highly sensitive fluorescence probes for protease and glycosidase based on precisely controlled spirocyclization. J Am Chem Soc. 2013 Jan 9;135 (1) :409-14.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Frequently Asked Questions
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