Closed-HMRG

Closed-HMRG is HMRG with closed spirocyclic structure. Ac-HMRG, an acetylated derivative of Hydroxymethyl rhodamine green, exists as a closed spirocyclic structure in aqueous solution at physiological pH, whereas HMRG itself takes an open nonspirocyclic structure. Ac-HMRG is colorless and nonfluorescent and HMRG is strongly fluorescent[1].

Product Specifications

CAS Number

[7449-51-6]

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Assay Protocol

https://www.medchemexpress.com/closed-hmrg.html

Smiles

NC1=CC=C2C(OC3=CC(N)=CC=C3C24OCC5=C4C=CC=C5)=C1

Molecular Formula

C20H16N2O2

Molecular Weight

316.35

References & Citations

[1]Masayo Sakabe, et al. Rational design of highly sensitive fluorescence probes for protease and glycosidase based on precisely controlled spirocyclization. J Am Chem Soc. 2013 Jan 9;135 (1) :409-14.