Acoziborole
Acoziborole (SCYX-7158) is an effective, safe and orally active antiprotozoal agent for the research of human african trypanosomiasis (HAT) . In the T. b. brucei S427 strain, the MIC value for SCYX-7158 is 0.6 μg/mL[1].
Product Specifications
CAS Number
[1266084-51-8]
Product Name Alternative
SCYX-7158; AN5568
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Acoziborole.html
Purity
99.70
Solubility
DMSO : ≥ 125 mg/mL
Smiles
O=C(NC1=CC=C2C(C)(C)OB(O)C2=C1)C3=CC=C(F)C=C3C(F)(F)F
Molecular Formula
C17H14BF4NO3
Molecular Weight
367.10
References & Citations
[1]Jacobs RT, et al. SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis. PLoS Negl Trop Dis. 2011 Jun;5 (6) :e1151.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
Trypanosoma
Available Sizes
Curated Selection
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