Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Efaroxan (hydrochloride)

Efaroxan hydrochloride is a potent, selective and orally active α2-adrenoceptor antagonist, with antidiabetic activity. Efaroxan hydrochloride is a selective I1-Imidazoline receptor antagonist. Efaroxan hydrochloride can be used for the research of cardiovascular disease[1][2][3].

Product Specifications

CAS Number

89197-00-2

UNSPSC

12352005

Hazard Statement

H301

Target

Adrenergic Receptor; Imidazoline Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/efaroxan-hydrochloride.html

Purity

99.80

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CCC1(C2=NCCN2)OC3=CC=CC=C3C1.[H]Cl

Molecular Formula

C13H17ClN2O

Molecular Weight

252.74

Precautions

H301

References & Citations

[1]T L Berridge, et al. Selectivity profile of the alpha 2-adrenoceptor antagonist efaroxan in relation to plasma glucose and insulin levels in the rat. Eur J Pharmacol. 1992 Mar 24;213 (2) :205-12.|[2]A O Abdel-Zaher, et al. The potential antidiabetic activity of some alpha-2 adrenoceptor antagonists. Pharmacol Res. 2001 Nov;44 (5) :397-409.|[3]T L Berridge, et al. Comparison of the effects of efaroxan and glibenclamide on plasma glucose and insulin levels in rats. Eur J Pharmacol. 1992 Mar 24;213 (2) :213-8.|[4]Berridge TL, et al. Selectivity profile of the alpha 2-adrenoceptor antagonist efaroxan in relation to plasma glucose and insulin levels in the rat. Eur J Pharmacol. 1992 Mar 24;213 (2) :205-12.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

α adrenergic receptor

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

GF-1 Plasmid DNA Extraction Kit (RNase A included), 100 preps
GF-PL-100 100 Preparations

GF-1 Plasmid DNA Extraction Kit (RNase A included), 100 preps

Sign In for Pricing
View Details
SARS-CoV-2 Nucleocapsid protein (P13L, R203K, G204R, G214C), His Tag
NUN-C52Ha-1mg 1 mg

SARS-CoV-2 Nucleocapsid protein (P13L, R203K, G204R, G214C), His Tag

Sign In for Pricing
View Details
Smok3b Mouse Gene Knockout Kit (CRISPR)
KN516342 1 Kit

Smok3b Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
GOLGA8CP Antibody
KC-43507-01 50 μL

GOLGA8CP Antibody

Sign In for Pricing
View Details
GOLGA8CP Antibody
KC-43507-02 100 µL

GOLGA8CP Antibody

Sign In for Pricing
View Details
GOLGA8CP Antibody
KC-43507-03 1 mL

GOLGA8CP Antibody

Sign In for Pricing
View Details