N6-Etheno 2'-deoxyadenosine

N6-Etheno 2'-deoxyadenosine is a reactive oxygen species (ROS) /reactive nitrogen species (RNS) -induced DNA oxidation product, used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues[1].

Product Specifications

CAS Number

[68498-25-9]

UNSPSC

12352005

Target

Endogenous Metabolite; Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/N6-Etheno_2_acute_-deoxyadenosine.html

Purity

99.48

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 7.14 mg/mL (ultrasonic)

Smiles

O[C@@H](C1)[C@@H](CO)O[C@H]1N(C=N2)C3=C2C4=NC=CN4C=N3

Molecular Formula

C12H13N5O3

Molecular Weight

275.27

References & Citations

[1]Gao L, et al. DNA Product Formation in Female Sprague-Dawley Rats Following Polyhalogenated Aromatic Hydrocarbon (PHAH) Exposure. Chem Res Toxicol. 2017 Mar 20;30 (3) :794-803.