(Rac) -Ketoconazole
(Rac) -Ketoconazole ((Rac) -R 41400) is an antifungal imidazole compound with oral activity. (Rac) -Ketoconazole interferes with ergosterol synthesis by inhibiting cytochrome P450-dependent 14α-sterol demethylase (CYP51), a key enzyme on the fungal cell membrane, leading to membrane dysfunction and ultimately inhibition of fungal growth and reproduction. (Rac) -Ketoconazole is indicated for studies of fungal infections[1].
Product Specifications
CAS Number
[79156-75-5]
Product Name Alternative
(Rac) -Ketoconazol; (Rac) -R 41400
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Cytochrome P450; Fungal
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/rac-ketoconazole.html
Smiles
CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl
Molecular Formula
C26H28Cl2N4O4
Molecular Weight
531.43
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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