Zopiclone N-oxide

Zopiclone N-oxide (RP 29753) is a less active metabolite of Zopiclone. Zopiclone N-oxide is also an impurity of Eszopiclone and is formed by the oxidation of Eszopiclone[1][2].

Product Specifications

CAS Number

[43200-96-0]

Product Name Alternative

RP 29753

UNSPSC

12352005

Hazard Statement

H302, H336, H411

Target

Drug Metabolite; GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/zopiclone-n-oxide.html

Purity

98.0

Solubility

DMSO : 16.67 mg/mL (ultrasonic)

Smiles

O=C(N1CC[N+](C)([O-])CC1)OC2N(C3=NC=C(Cl)C=C3)C(C4=NC=CN=C42)=O

Molecular Formula

C17H17ClN6O4

Molecular Weight

404.81

Precautions

H302, H336, H411

References & Citations

[1]C Fernandez, et al. Pharmacokinetics of zopiclone and its enantiomers in Caucasian young healthy volunteers. Drug Metab Dispos. Nov-Dec 1993;21 (6) :1125-8.|[2]Yu Sha, et al. Synthesis of RP 48497, an impurity of eszopiclone. Molecules. 2008 Aug 22;13 (8) :1817-21.