Endochin
Endochin is an antimalarial agent. Endochin inhibits T.gondii with an IC50 of 0.003 nM. Endochin is also active against experimental toxoplasmosis[1][2].
Product Specifications
CAS Number
354155-51-4
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/endochin.html
Purity
99.41
Solubility
10 mM in DMSO
Smiles
O=C1C(CCCCCCC)=C(C)NC2=C1C=CC(OC)=C2
Molecular Formula
C18H25NO2
Molecular Weight
287.40
References & Citations
[1]Doggett JS, et al. Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosis. Proc Natl Acad Sci U S A. 2012 Sep 25;109 (39) :15936-41. |[2]Cross RM, et al. Endochin optimization: structure-activity and structure-property relationship studies of 3-substituted 2-methyl-4 (1H) -quinolones with antimalarial activity. J Med Chem. 2010 Oct 14;53 (19) :7076-94.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Plasmodium
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