Endochin

Endochin is an antimalarial agent. Endochin inhibits T.gondii with an IC50 of 0.003 nM. Endochin is also active against experimental toxoplasmosis[1][2].

Product Specifications

CAS Number

[354155-51-4]

UNSPSC

12352005

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/endochin.html

Purity

99.41

Solubility

10 mM in DMSO

Smiles

O=C1C(CCCCCCC)=C(C)NC2=C1C=CC(OC)=C2

Molecular Formula

C18H25NO2

Molecular Weight

287.40

References & Citations

[1]Doggett JS, et al. Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosis. Proc Natl Acad Sci U S A. 2012 Sep 25;109 (39) :15936-41. |[2]Cross RM, et al. Endochin optimization: structure-activity and structure-property relationship studies of 3-substituted 2-methyl-4 (1H) -quinolones with antimalarial activity. J Med Chem. 2010 Oct 14;53 (19) :7076-94.