Topoisomerase II inhibitor 20
Selected Variant
HY-158061-01
Size: 5 mg
Topoisomerase II inhibitor 20 (Compound 3e) is a potent topoisomerase II (Topoisomerase II) inhibitor with an IC50 of 0.98 µM. Topoisomerase II inhibitor 20 induces apoptosis and has broad-spectrum anticancer activity[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; Topoisomerase
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/topoisomerase-ii-inhibitor-20.html
Purity
98.44
Solubility
DMSO : 4 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CN(CC)C2=C(C=C(F)C(N3CC(C)NCC3)=C2F)C1=O)N/N=C/C4=CC=CS4
Molecular Formula
C22H23F2N5O2S
Molecular Weight
459.51
References & Citations
[1]Adly ME, et al. Design, synthesis and in vitro anticancer activity of some new lomefloxacin derivatives. Sci Rep. 2024 Mar 14;14 (1) :6175
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Topo II
Available Sizes
Price
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CD63 (Late Endosomes Marker) (LAMP3/2881), CF405S conjugate, 0.1mg/mL
Anti-LSM8 Antibody Picoband® (monoclonal, 6B11)-iFluor647 Conjugate
ZNF690 / ZSCAN29 (ZSCAN29/2610), CF647 conjugate, 0.1mg/mL
Anti-Mast Cell Chymase/CMA1 Antibody Picoband®, Dylight550 Conjugate
