PARP7-IN-17
PARP7-IN-17 is a potent inhibitor of PARP7 with IC50 of 4.5 nM that has oral bioavailability. PARP7-IN-17 displays antitumor effect[1].
Product Specifications
CAS Number
3024030-10-9
UNSPSC
12352005
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/parp7-in-17.html
Purity
99.81
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CC2=CN(N=C21)[C@@H](C)C(N3CCN(CC3)C4=NC=C(C=N4)C(F)(F)F)=O)N
Molecular Formula
C20H20F3N7O2
Molecular Weight
447.41
References & Citations
[1]Hongfeng Gu, et al. Discovery of Highly Selective PARP7 Inhibitors with a Novel Scaffold for Cancer Immunotherapy. J Med Chem. 2023 Dec 7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PARP7
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TP309090M 100 µg
Phosphoserine phosphatase (PSPH) (NM_004577) Human Recombinant Protein
Sign In for Pricing
View Details 
![MAX Mouse Monoclonal Antibody [Clone ID: OTI14G1]](https://cdn.genprice.uk/products/937/68dd18bc061270361e909174/imageurl/cf815026.webp)
