BI-3812
BI-3812, a chemical probe, is a highly efficient BCL6 inhibitor that is capable of suppressing the BTB domain of BCL6, with an IC50 value of ≤ 3 nM, exhibiting antitumor activity[1].
Product Specifications
CAS Number
2166387-64-8
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/BI-3812.html
Concentration
10mM
Purity
99.72
Solubility
DMSO : 20.83 mg/mL (ultrasonic)
Smiles
ClC1=CN=C(N2CCC(C(N(C)C)=O)CC2)N=C1NC3=CC(C=C(OCC(NC)=O)C(N4C)=O)=C4C(OC)=C3
Molecular Formula
C26H32ClN7O5
Molecular Weight
558.03
Precautions
H315, H319, H320
References & Citations
[1]Kerres N, et al. Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6. Cell Rep. 2017 Sep 19;20 (12) :2860-2875.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Carbonic Anhydrase IX (CA9) Human Gene Knockout Kit (CRISPR)
