4-Azido-L-phenylalanine

4-Azido-L-phenylalanine is an unnatural amino acid, which is used as an effective vibrational reporter of local protein environments. 4-Azido-L-phenylalanine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

[33173-53-4]

Product Name Alternative

P-Azidophenylalanine; p-Azido-L-phenylalanine

UNSPSC

12352005

Hazard Statement

H242

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/4-Azido-L-phenylalanine.html

Purity

99.84

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; adjust pH to 3 with HCl; heat to 80°C)

Smiles

O=C(O)[C@@H](N)CC1=CC=C(N=[N+]=[N-])C=C1

Molecular Formula

C9H10N4O2

Molecular Weight

206.20

Precautions

H242

References & Citations

[1]Albayrak C, et al. Cell-free co-production of an orthogonal transfer RNA activates efficient site-specific non-natural amino acid incorporation. Nucleic Acids Res. 2013 Jun;41 (11) :5949-63.