Rabbit anti-LAG3 Monoclonal Antibody

<strong>Rabbit anti-LAG3 Monoclonal Antibody</strong>_x000D_ <strong>Catalog number:</strong> B2015578_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µL_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8¬∞C_x000D_ <strong>Keywords:</strong> CD antigen CD223;CD223;LAG-3;Ly66;lymphocyte activation gene 3 protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Carlino MS, Larkin J, Long GV. Immune checkpoint inhibitors in melanoma Lancet. 2021 Sep 11;398(10304):1002-1014._x000D_ 2: FDA approves anti-LAG3 checkpoint Nat Biotechnol. 2022 May;40(5):625._x000D_ 3: Bae J, Accardi F, Hideshima T, Tai YT, Prabhala R, Shambley A, Wen K, Rowell S, Richardson PG, Munshi NC, Anderson KC. Targeting LAG3/GAL-3 to overcome immunosuppression and enhance anti-tumor immune responses in multiple myeloma Leukemia. 2022 Jan;36(1):138-154._x000D_ 4: Andrews LP, Cillo AR, Karapetyan L, Kirkwood JM, Workman CJ, Vignali DAA. Molecular Pathways and Mechanisms of LAG3 in Cancer Therapy Clin Cancer Res. 2022 Dec 1;28(23):5030-5039._x000D_ 5: Mulholland M, Kritikou E, Katra P, Nilsson J, Bj√∂rkbacka H, Lichtman AH, Rodriguez A, Engelbertsen D. LAG3 Regulates T Cell Activation and Plaque Infiltration in Atherosclerotic Mice JACC CardioOncol. 2022 Dec 20;4(5):635-645._x000D_ 6: Lauder SN, Vanhaesebroeck B, Gallimore A. Sequential targeting of PI3KŒ¥ and LAG3 as an effective anti-cancer approach Br J Cancer. 2021 Aug;125(4):467-469._x000D_ 7: Pang XQ, Li X, Zhu WH, Huang RK, Mo ZS, Huang ZX, Zhang Y, Xie DY, Gao ZL. LAG3(+) erythroid progenitor cells inhibit HBsAg seroclearance during finite pegylated interferon treatment through LAG3 and TGF-Œ≤ Antiviral Res. 2023 May;213:105592._x000D_ 8: Warren PD, Dodson MS, Smith MH, Landowski TH, Palting JD, Towne P. High-Resolution Epitope Mapping and Affinity Binding Analysis Comparing a New Anti-Human LAG3 Rabbit Antibody Clone to the Commonly Used Mouse 17B4 Clone Antibodies (Basel). 2022 Sep 21;11(4):60._x000D_ 9: Ascione A, Arenaccio C, Mallano A, Flego M, Gellini M, Andreotti M, Fenwick C, Pantaleo G, Vella S, Federico M. Development of a novel human phage display-derived anti-LAG3 scFv antibody targeting CD8(+) T lymphocyte exhaustion BMC Biotechnol. 2019 Oct 17;19(1):67._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/34859232">10: Wang J, Tawbi HA. Emergent immunotherapy approaches for brain metastases Neurooncol Adv. 2021 Nov 27;3(Suppl 5):v43-v51. </a>_x000D_ _x000D_ <strong>Products Related to Rabbit anti-LAG3 Monoclonal Antibody can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>