Purified Anti-Human CD80 Antibody[2D10]
Product Specifications
Background
B7-1 and B7-2, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20‑100 fold higher affinity than CD28 and is involved in the down‑regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages.
Abbreviation
CD80
Gene ID
941
UniProt
P33681
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD80 protein
Target
LAB; CTLA-4 counter-receptor B; T-lymphocyte activation antigen CD; B7; B7-1; B7.1; BB1; CD28LG; CD28LG1; LAB7; CD80; CD28LGB7-1 antigen; T-lymphocyte activation antigen CD80; Activation B7-1 antigen; CTLA-4 counter-receptor B7.1; B7-1; BB1; B lymphocyte activation antigen B7; B7-1 antigen; B7-1 antigen) ; CD28 antigen ligand 1; CD80 antigen; CD80 antigen (CD28 antigen ligand 1; CD80 molecule; Costimulatory factor CD80; costimulatory molecule variant IgV-CD80
Clonality
Monoclonal
Clone
2D10
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology; Stem Cells
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotype
Mouse IgG1, κ
Available Sizes
Curated Selection
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