Avenanthramide A
Product Specifications
Product Name Alternative
Monobromobimane
UNSPSC Description
Avenanthramide A is a phytoalexin, which can be found in oats (Avena sativa L.). Avenanthramide A targets the RNA helicase DDX3, leads to mitochondrial swelling and increased ROS production, and induces apoptosis in CRC cells. Avenanthramide A exhibits antitumor efficacy in mouse model. Avenanthramide A orally active[1].
Target Antigen
Apoptosis; Reactive Oxygen Species
Type
Natural Products
Related Pathways
Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/avenanthramide-a.html
Purity
99.20
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(O)=CC=C1NC(/C=C/C2=CC=C(C=C2)O)=O)O
Molecular Weight
299.28
References & Citations
[1]Fu R, et al., Avenanthramide A triggers potent ROS-mediated anti-tumor effects in colorectal cancer by directly targeting DDX3. Cell Death Dis. 2019 Aug 7;10(8):593.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-114977/Avenanthramide-A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114977/Avenanthramide-A-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
108605-70-5
Available Sizes
Curated Selection
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