Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

ZLJ-6

ZLJ-6 is a dual COX and 5-LOX inhibitor with oral activity. The IC50 values for COX-1, COX-2 and 5-LOX were 0.73, 0.31 and 0.99 μM, respectively. ZLJ-6 has anti-inflammatory and analgesic activity[1][1].

Product Specifications

UNSPSC

12352005

Target

COX; Lipoxygenase

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/zlj-6.html

Solubility

10 mM in DMSO

Smiles

CS(=O)(O)=O.CN(C(N)=NC/1=O)C1=C/C2=CC=C(C=C2)S(C)(=O)=O

Molecular Formula

C13H17N3O6S2

Molecular Weight

375.42

References & Citations

[1]Li L, et al. The anti-inflammatory effects of ZLJ-6, a novel dual cyclooxygenase/5-lipoxygenase inhibitor. Eur J Pharmacol. 2009 Apr 1;607 (1-3) :244-50.|[2]Chen L, et al. ZLJ-6, a novel COX/5-LOX inhibitor, attenuates TNF-α-induced endothelial E-selectin, ICAM-1 and VCAM-1 expression and monocyte-endothelial interactions via a COX/5-LOX-independent mechanism. Vascul Pharmacol. 2011 Nov-Dec;55 (5-6) :135-42.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-113807/ZLJ-6-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-113807/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-LOX; COX-1; COX-2

CAS Number

[1051931-39-5]

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Mouse Anti-Human MART-1 (Melan A) monoclonal antibody, clone JID519
CABT-L2926-01 100 µl, 500 µl

Mouse Anti-Human MART-1 (Melan A) monoclonal antibody, clone JID519

Ask
View Details
Mouse Anti-Human MART-1 (Melan A) monoclonal antibody, clone JID519
CABT-L2926-02 100 uL, 500 uL

Mouse Anti-Human MART-1 (Melan A) monoclonal antibody, clone JID519

Ask
View Details
Magnesium Enzymatic 336mL (6x44mL + 6x12mL)
B46310 336 mL (6x 44 mL + 6x 12 mL)

Magnesium Enzymatic 336mL (6x44mL + 6x12mL)

Ask
View Details
Mad2l2 3'UTR Lenti-reporter-Luc Vector
27892084 1.0 μg

Mad2l2 3'UTR Lenti-reporter-Luc Vector

Ask
View Details
ACE2 Antibody
E300498-01 100 µg

ACE2 Antibody

Ask
View Details
ACE2 Antibody
E300498-02 100 µg - 200 µL

ACE2 Antibody

Ask
View Details