ICAM-1-IN-1
ICAM-1-IN-1 is a potent and selective inhibitor of E-selectin and ICAM-1 with IC50 values of 7 and 5 nM, respectively.
Product Specifications
CAS Number
251994-14-6
UNSPSC
12352005
Target
Integrin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Thieno[2,3-c]pyridine-2-carboxamide,_4-_4-bromophenoxy_-N-methyl-.html
Purity
99.73
Solubility
DMSO : ≥ 135 mg/mL
Smiles
O=C(C(S1)=CC2=C1C=NC=C2OC3=CC=C(Br)C=C3)NC
Molecular Formula
C15H11BrN2O2S
Molecular Weight
363.23
References & Citations
[1]Zhu GD, et al. Selective inhibition of ICAM-1 and E-selectin expression in human endothelial cells. 2. Arylmodifications of 4- (aryloxy) thieno[2,3-c]pyridines with fine-tuning at C-2 carbamides. J Med Chem. 2001 Oct 11;44 (21) :3469-87.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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