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Atriopeptin III (rat)

Atriopeptin III (ANP 127-150) (rat), a 24-amino acid atrial peptide, is a potent vasodilator and natriuretic/diuretic agent. Atriopeptin III (rat) improves renal functions and decreases blood pressure in a ureter-obstructed rat kidney model. Atriopeptin III (rat) can be used for research of chronic renal failure[1].

Product Specifications

CAS Number

90817-13-3

Product Name Alternative

ANP 127-150 (rat)

UNSPSC

12352209

Target

Natriuretic Peptide Receptor (NPR)

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/atriopeptin-iii-rat.html

Solubility

10 mM in DMSO

Smiles

OC(C=C1)=CC=C1C[C@@H](C(O)=O)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@@H]2CSSC[C@@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@@](C(N[C@H](C(N[C@H](C(N[C@@](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N2)=O)=O)CC(C)C)=O)=O)CO)=O)CCC(N)=O)=O)C)=O)=O)([H])[C@@H](C)CC)=O)CCCNC(N)=N)=O)CC(O)=O)=O)([H])[C@@H](C)CC)=O)CCCNC(N)=N)=O)=O)=O)CC3=CC=CC=C3)=O)NC([C@H](CO)NC([C@@H](N)CO)=O)=O)=O)=O)=O)CC4=CC=CC=C4)=O)=O

Molecular Formula

C107H165N35O34S2

Molecular Weight

2549.80

References & Citations

[1]Olsen UB, et al. Atriopeptin III improves renal functions in a ureter-obstructed rat kidney model. Eur J Pharmacol. 1986 Mar 18;122 (2) :191-6.|[2]Cole BR, et al. Atriopeptin III. A potent natriuretic, diuretic, and hypotensive agent in rats with chronic renal failure. J Clin Invest. 1985 Dec;76 (6) :2413-5.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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