Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Tempo

Tempo is a nitric oxide radical and a selective scavenger of ROS in mitochondria. Tempo is also an organocatalyst that disproportionates superoxide and oxidizes primary alcohols to aldehydes in a catalytic cycle. Tempo has mutagenic and antioxidant effects and can induceDNA strand breaks. Tempo also exerts cytotoxic and mutagenic properties in mouse lymphoma cells[1][2][3][4].

Product Specifications

CAS Number

2564-83-2

UNSPSC

12352005

Hazard Statement

H314, H412

Target

DNA/RNA Synthesis; Mitochondrial Metabolism; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tempo.html

Purity

99.92

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

[O]N1C(C)(C)CCCC1(C)C

Molecular Formula

C9H18NO

Molecular Weight

156.25

Precautions

H314, H412

References & Citations

[1]Chen X, et al. Isocitrate dehydrogenase 2 contributes to radiation resistance of oesophageal squamous cell carcinoma via regulating mitochondrial function and ROS/pAKT signalling. Br J Cancer. 2020 May 5.|[2]Kaur G, et al. Eugenol precludes cutaneous chemical carcinogenesis in mouse by preventing oxidative stress and inflammation and by inducing apoptosis. Mol Carcinog. 2010 Mar;49 (3) :290-301.|[3]Guo X, et al. Comparative Genotoxicity of TEMPO and 3 of Its Derivatives in Mouse Lymphoma Cells. Toxicol Sci. 2018 May 1;163 (1) :214-225.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

CD63 Double Nickase Plasmid (m)
sc-419564-NIC 20 µg

CD63 Double Nickase Plasmid (m)

Sign In for Pricing
View Details
USP2 Protein Vector (Mouse) (pPM-C-HA)
PV244492 500 ng

USP2 Protein Vector (Mouse) (pPM-C-HA)

Sign In for Pricing
View Details
C / EBP delta / epsilon Blocking Peptide
abx062412-01 1 mg

C / EBP delta / epsilon Blocking Peptide

Sign In for Pricing
View Details
C / EBP delta / epsilon Blocking Peptide
abx062412-02 5 mg

C / EBP delta / epsilon Blocking Peptide

Sign In for Pricing
View Details
Acetylthiocholine chloride
A10240-01 1 g

Acetylthiocholine chloride

Sign In for Pricing
View Details
Acetylthiocholine chloride
A10240-02 5 g

Acetylthiocholine chloride

Sign In for Pricing
View Details